Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infection

Manuscript:Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in <i>Staphylococcus aureus</i> infection<br>Bartsch et al. 2022<br><b>Processed and filtered (meta) scRNA-seq data</b>For raw (unfiltered) datasets, seehttps://doi.org/10.6084/m9.figshare.14935458.v2<b><br></b>https://doi.org/10.6084/m9.figshare.19355459.v1<br><b><br></b>Mice Genotype:Figure 4: C57BL/6 IL17A^Crex Rosa26^eYFPx Tbx21^wtFigure 5: combined and annotated data from C57BL/6 IL17A^Crex Rosa26^eYFPx Tbx21^flox<br>C57BL/6 IL17A^Crex Rosa26^eYFPx Tbx21^wtOrgan: Kidney<br>Cells: FACS-sorted CD45⁺CD3⁺CD4⁺eYFP⁺Files:1. <i>Bartsch2022_Figure4_Tbx21WT_filtered_count_matrix.csv</i>: (380.65 MB) CSV Data; Matrix; UMI-Counts; columns: annotated barcodes; rows: mice gene symbols2. <i>Bartsch2022_Figure4_Tbx21WT_meta_data.csv: (</i>572.71 kB)CSV Data; Meta Data; columns: barcodes, cluster annotation, pseudotime of lineage Th17-&gt;Th1, umap dimension 1, map dimension 23. <i>Bartsch2022_Figure5_combined_Tbx21wt_ko_filtered_count_matrix.csv: (</i>526.34 MB)CSV Data; Matrix; UMI-Counts; columns: annotated barcodes; rows: mice gene symbols4. <i>Bartsch2022_Figure5_combined_Tbx21wt_ko_meta_data.csv:(</i>790.91 kB)<i> </i>CSV Data; Meta Data; columns: barcodes, annotation, origIdent (Tbx21wt vs Tb21ko (see mice genotype)), cluster, umap dimension 1, map dimension 2