Reciprocal regulation of EGR1 and EZH2 in breast cancer cells
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https://www.ncbi.nlm.nih.gov/sra/SRP216394
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资源简介:
We found that EGR1 stimulates the expression of EZH2, which in turn inhibited the expression of EGR1 through a silencer region and deletion of the silencer resulted in upregulation of EGR1, which reduced the malignancy of breast cancer cells. Overall design: RNA sequencing of MDA-MB-231 and MCF-7 with wildtype and silencer knockout. Two clones of silencer knockout were included.
创建时间:
2020-09-25



