Previously, lncRNA Malat1 knockout mice were generated by insertional inactivation. By crossing this line to MMTV-PyMT mammary tumor mouse model, we produced PyMT;Malat1 wild-type (WT) and PyMT;Malat1
Gene expression profiles of the cells composing the dorsal skin of young control and YAP/TAZ knockout mice with the skin of a old mouse. Overall design: Single cell profiles were derived from the dors
The NF2 gene, which encodes the Merlin protein, is a bona fide tumor suppressor whose mutations underlie inherited tumor syndrome Neurofibromatosis Type 2 (NF2). Recent large-scale genome sequencing s
Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy, with chem-otherapy resistance representing a major therapeutic challenge. Emerging evidence suggests that ferroptosis, an iro