Organocatalytic Enantioselective Cascade Michael−Michael−Wittig Reactions of Phosphorus Ylides: One-Pot Synthesis of the <i>all</i>-<i>cis</i> Trisubstituted Cyclohexenecarboxylates via the [1 + 2 + 3] Annulation
收藏NIAID Data Ecosystem2026-03-06 收录
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The stereoselective synthesis of all-cis 5-nitro-4,6-diphenylcyclohex-1-enecarboxylic ester has been achieved by an organocatalytic asymmetric Michael−Michael−Wittig cascade reaction of phosphorus ylides, nitroolefins, and α,β-unsaturated aldehydes with excellent enantioselectivities (up to >99% ee).
创建时间：
2016-02-25
