官方服务：
资源简介：
The RtcB RNA ligase is an essential component of the metazoan unfolded protein response.
应用场景：
相关数据集
N-octanoyl dopamine treatment of endothelial cells induces the unfolded protein response and results in hypometabolism and tolerance to hypothermia
N-octanoyl dopamine (NOD), but not dopamine dose dependently induces the UPR. This was also found for other synthetic N-Acyl dopamine derivates (NADD). Induction of the UPR was dependent on the redox
NIAID Data Ecosystem70
Mitochondrial aconitase inhibits immunity via reducing mitochondrial unfolded protein response. Mitochondrial aconitase inhibits immunity via reducing mitochondrial unfolded protein response
We show that mitochondrial aconitase, ACO-2, a Krebs cycle enzyme that catalyzes the conversion of citrate to isocitrate, inhibits immunity against pathogenic bacteria in C. elegans. We found that gen
NIAID Data Ecosystem30
The effect of SubAB treatment on Wnt-High and Wnt-Low sorted human colon cancer stem cells
The effect of ER-stress and subsequent activation of the unfolded protein response was investigated in colon cancer stem cells and more differentiated colon cancer cells Human colon cancer derived sph
NIAID Data Ecosystem10
Contribution of the Unfolded Protein Response (UPR) transcription factor XBP1 to brain aging
In this project we aimed to evaluate the contribution of endoplasmic reticulum stress sensor IRE1 and its downstream transcription factor XBP1s to mammalian brain aging. We compared traits associated
NIAID Data Ecosystem70
WP4925 - Unfolded protein response - Homo sapiens
The unfolded protein response (UPR) pathway regulates and protects the cell from improperly folded protein overload in the endoplasmic reticulum (ER). UPR can result in the slowing of protein synthesi
NIAID Data Ecosystem10
