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Dasatinib Overcomes Glucocorticoid Resistance in B-cell Acute Lymphoblastic Leukemia

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214319
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Bulk RNA-Seq of sorted B cell populations revealed glucocorticoid pathway being coordinated with B-cell development. Bulk RNA-Seq of human BCP-ALL cell lines treated with dexamethasone identified pathways of resistance. Comparative gene expression profiling analysis of RNA-seq data for B-cell sorted populations in 3 heathy donors and cell lines (NALM6, REH wt and REH GCR) treated with vehicle or dexamethasone.
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2023-07-03
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