Scoring output for FA associated proteins.

*NLS and pI based on longest peptide. The relatively large difference in percentage identity between human-mouse and mouse-human of FAN1/MTMR15 indicates a difference in sequence length. Indeed, upon manually checking the length for the human MTMR15 protein turned out to be 1017 aa (ENSP00000354497) and for the mouse ortholog 743 aa (ENSMUSP00000103138). When interrogating the FAN1 ortholog at NCBI HomoloGene, both proteins were of similar length and an identity score of 71% was predicted for human-mouse and mouse-human (Human: NP_055782.3, Mouse: NP_808561.2). The missing or wrong orthologs in EnsEMBL also contribute to the lower scoring of FAAP16 (human-mouse 78% amino acid identity; mouse-human 83% amino acid identity) and FAAP20 (human-mouse 53% amino acid identity; mouse-human 53% amino acid identity) and FAAP10 (human-mouse 64% amino acid identity; mouse-human 64% amino acid identity) when interrogating the orthologs at NCBI HomoloGene.