Detection of the expression profiles of mRNA and miRNA between dermal papilla cells and hair matrix cells of yak hair follicle [RNA-seq]

Dermal papilla cells (DPCs) and epidermal hair matrix cells (HMCs) located in hair bulb are the key cell types during the hair follicles (HFs) development. To explore the mRNA and miRNA expression of DPCs and HMCs of yak hair follicle, illustrating the mocular basis of the interaction and cellular communication between DPCs and HMCs during the hair follicle development, the DPCs and HMCs of yak were isolated and cultured, RNA-seq was used to identify the differentially expressed mRNAs and miRNAs between DPCs and HMCs. The dermal papilla cells (DPCs) and hair matrix cells (HMCs) from yak skin were isolated and cultured. Then a total of six samples, including three DPCs and three HMCs samples were used to RNA sequencing.