The main pharmacokinetic parameters of Compound 1 after oral administration at 45, 180 and 720/kg of Compound 1 in Wistar rats (mean ± S.D., n = 6).
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t1/2, half-life; Ke: elimination rate constant; Tmax: time of peak concentration; Cmax: maximum concentration; AUC0–96: area under the curve up to 96 h; AUC0–∞, area under the total concentration-time curve; MRT, mean residence time; CL, systemic clearance; Vd, steady-state volume of distribution. *P
创建时间：
2015-12-02
