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Development and Preclinical Efficacy of Novel Transforming Growth Factor-β1 (TGFβ1) siRNAs for Pulmonary Fibrosis

ChEBI2011-11-22 更新2026-07-21 收录

RNA干扰药物研发

纤维化治疗靶点

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-28122 数据链接链接失效反馈

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资源简介：

Development and Preclinical Efficacy of Novel Transforming Growth Factor-β1 (TGFβ1) siRNAs for Pulmonary Fibrosis

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创建时间：

2011-11-22

肽类抑制剂设计

纤维化治疗靶点

The increased remodeling of the extracellular matrix (ECM) in pulmonary fibrosis (PF) generates bioactive ECM fragments called matricryptins, which include elastin-derived peptides (EDPs). The interac

Figshare2024-04-08 更新70

Single versus double lung transplantation in pulmonary fibrosis: systematic review and meta-analysis of observational studies and datasets

移植疗效评估

纤维化治疗靶点

Systematic review protocol registration

DataCite Commons2020-08-03 更新30

Design and Synthesis of Novel Ultralong-Acting Peptides as EDP-EBP Interaction Inhibitors for Pulmonary Fibrosis Treatment

肽类药物设计

纤维化治疗靶点

NIAID Data Ecosystem20

DataSheet1_Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis.PDF

纤维化治疗靶点

糖酵解抑制

Idiopathic pulmonary fibrosis (IPF) is a fatal disease in which the normal alveolar network is gradually replaced by fibrotic scars. Current evidence suggests that metabolic alterations correlate with

NIAID Data Ecosystem30

An integrative multiomics framework for identification of therapeutic targets in pulmonary fibrosis [TimeSeries]. An integrative multiomics framework for identification of therapeutic targets in pulmonary fibrosis [TimeSeries]

纤维化治疗靶点

多组学整合分析

Pulmonary fibrosis (PF) is a progressive disease with a poor prognosis and lack of effective treatments. Therefore, identifying effective therapeutic modalities is required to improve outcome. However

NIAID Data Ecosystem30

Development and Preclinical Efficacy of Novel Transforming Growth Factor-β1 (TGFβ1) siRNAs for Pulmonary Fibrosis

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