Effect of the inferred FSHR gene haplotypes on tested male hormonal and testicular parameter distribution.

aFSHR gene haplotypes were inferred using genotype data on FSHR -29G/A (rs1394205; Table 2) and FSHR 2039 A/G (rs6166, Asn680Ser; Table S1; (16). Haplotype G-Asn is the combination of G- and Asn-alleles at the FSHR positions -29G/A and Asn680Ser, respectively, etc.bP-value from omnibus test estimating the overall effect of FSHR haplotypes on tested parameter distribution [30] (http://pngu.mgh.harvard.edu/~purcell/plink/).cCorrected empirical P-value from haplotype-based association test for individual haplotypes after correction for multiple haplotypes using max(T) permutation procedure (number of permutations, n = 10,000).dEffect of individual haplotypes is shown as the estimated linear regression (additive model) coefficient, β.eAmong Estonian oligozoospermic infertile patients, Inhibin B values were available for 264 individuals.