Crystal Structure of Human IDH1 R132H Mutant in Complex with NADPH and Compound IHMT-IDH1-053
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Crystal Structure of Human IDH1 R132H Mutant in Complex with NADPH and Compound IHMT-IDH1-053 Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, ... Authors: Guo, G, Wang, B, Liu, J, Liu, Q. Deposit date: 2022-10-27 Release date: 2023-05-24 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure-based discovery of IHMT-IDH1-053 as a potent irreversible IDH1 mutant selective inhibitor. Eur.J.Med.Chem., 256, 2023
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2022-10-27
