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Synthesis, Structure, and Antiproliferative Activity of Ruthenium(II) Arene Complexes with N,O-Chelating Pyrazolone-Based β‑Ketoamine Ligands

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/Synthesis_Structure_and_Antiproliferative_Activity_of_Ruthenium_II_Arene_Complexes_with_N_O_Chelating_Pyrazolone_Based_Ketoamine_Ligands/2225491
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资源简介:
Novel ruthenium half-sandwich complexes containing (N,O)-bound pyrazolone-based β-ketoamine ligands have been prepared, and the solid-state structures of one ligand and five complexes have been determined by single-crystal X-ray diffraction. Some of the complexes display moderate cytotoxicity toward the human ovarian cancer cell lines A2780 and A2780cisR, the latter line having acquired resistance to cisplatin.
创建时间:
2014-12-15
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