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Suggested NI margin M3 for different scales of trial outcomes.

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NIAID Data Ecosystem2026-03-08 收录
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https://figshare.com/articles/dataset/_Suggested_NI_margin_M3_for_different_scales_of_trial_outcomes_/1123614
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Sample sizes are calculated according to Farrington and Manning [28] (for binary outcome), Rothmann [29] (continuous) and Crisp and Curtis [27] (survival). *overall number of events required. **The sample size is calculated for a two-arm trial with 1∶1 randomisation comparing the lower bound of a two-sided 95% CI with the margin.
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2014-07-31
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