Suggested NI margin M3 for different scales of trial outcomes.
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Sample sizes are calculated according to Farrington and Manning [28] (for binary outcome), Rothmann [29] (continuous) and Crisp and Curtis [27] (survival). *overall number of events required. **The sample size is calculated for a two-arm trial with 1∶1 randomisation comparing the lower bound of a two-sided 95% CI with the margin.
创建时间：
2014-07-31
