KLF1 null neonates display hydrops fetalis and a deranged erythroid transcriptome

ChEBI2015-01-01 更新2026-07-21 收录

红细胞生成障碍

基因功能缺失表型分析

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-60514 数据链接链接失效反馈

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KLF1 null neonates display hydrops fetalis and a deranged erythroid transcriptome

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2015-01-01

Data from: Evolutionary suppression of erythropoiesis via the modulation of TGF-β signaling in an Antarctic icefish

红细胞生成障碍

TGF-β信号通路

The Antarctic icefish, a family (Channichthyidae) of teleosts within the perciform suborder Notothenioidei, are the only known vertebrates without oxygen-transporting haemoglobins and that are large

DataCite Commons2025-06-01 更新110

Mutant SRSF2-associated impaired erythropoiesis is defined by increased mTORC1 signaling due to FYN missplicing

红细胞生成障碍

mTORC1信号通路

Using mouse models and primary human samples, we investigated the impact of SRSF2 mutations on erythropoiesis. We found reduced erythropoiesis in Srsf2P95H versus wild-type mice upon stress-induced er

NIAID Data Ecosystem30

Erythropoiesis Suppression Is Associated with Anthrax Lethal Toxin-Mediated Pathogenic Progression

炭疽杆菌致病机制

红细胞生成障碍

Anthrax is a disease caused by the bacterium Bacillus anthracis, which results in high mortality in animals and humans. Although some of the mechanisms are already known such as asphyxia, extensive kn

NIAID Data Ecosystem30

Additional file 2 of A synthetic ‘essentialome’ for axenic culturing of ‘Candidatus Liberibacter asiaticus’

植物病原体

基因功能缺失表型分析

Additional file 2: 120 unique ORFs present in the genome of L. crescens that are absent in the genomes of all sequenced ‘Ca. Liberibacter asiaticus’ strains.

NIAID Data Ecosystem40

Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1)

基因功能缺失表型分析

肾脏发育与免疫调节

Mice with inactivation of the gene encoding the suppressor of cytokine signaling-1 (SOCS-1) die in neonatal life with an IFN-γ-dependent inflammatory disease dominated by fatty degeneration and necros

PubMed Central2002-01-08 更新30

KLF1 null neonates display hydrops fetalis and a deranged erythroid transcriptome

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