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Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains in complex with a benzoxadiazole antagonist

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains in complex with a benzoxadiazole antagonist Descriptor: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine Authors: Scheuermann, T.H, Key, J, Tambar, U.K, Bruick, R.K, Gardner, K.H. Deposit date: 2012-08-07 Release date: 2013-02-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Allosteric inhibition of hypoxia inducible factor-2 with small molecules. Nat.Chem.Biol., 9, 2013
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2012-08-07
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