官方服务:
资源简介:
*Immunomodulators: azathioprine and/or infliximab.5-ASA- 5-amino salicylic acid.
应用场景:
创建时间:
2015-12-02
相关数据集
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease
Pharmacological inhibition of NLRP3 inflammasome activation may offer a new option in the treatment of inflammatory bowel disease. In this work, we report the design, synthesis, and biological screeni
NIAID Data Ecosystem60
Discovery of Potent and Selective Receptor-Interacting Serine/Threonine Protein Kinase 2 (RIPK2) Inhibitors for the Treatment of Inflammatory Bowel Diseases (IBDs)
Receptor-interacting serine/threonine protein kinase 2 (RIPK2) has been demonstrated to be a promising target for treating inflammatory diseases. Herein, we describe the discovery and optimization of
NIAID Data Ecosystem40
Data_Sheet_2_Coral-Derived Endophytic Fungal Product, Butyrolactone-I, Alleviates Lps Induced Intestinal Epithelial Cell Inflammatory Response Through TLR4/NF-κB and MAPK Signaling Pathways: An in vitro and in vivo Studies.ZIP
Herein, we assessed the anti-inflammatory and intestinal barrier protective effects of butyrolactone-I (BTL-1), derived from the coral-derived endophytic fungus (Aspergillus terreus), using the LPS-in
NIAID Data Ecosystem10
Anti Tumor Necrosis Factor Alpha Agents and Surgical Stress Response
Background: The immunologic response to stress is regulated by the cytokines. Anti-Tumor Necrosis Factor-α agents are antibodies directed against a key cytokine in the process angiogenesis and collage
NIAID Data Ecosystem40
A bile acids-GPBAR1 network supports anti-inflammatory and anti-fibrotic benefits of probiotics in colitis
Inflammatory bowel diseases (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), represent chronic relapsing conditions characterized by dysregulated immune responses, persistent inte
NIAID Data Ecosystem20



