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MOESM2 of Bead-based assays to simultaneously detect multiple human inherited blood disorders associated with malaria

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Mendeley Data2024-06-29 更新2024-06-30 收录
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https://springernature.figshare.com/articles/MOESM2_of_Bead-based_assays_to_simultaneously_detect_multiple_human_inherited_blood_disorders_associated_with_malaria/7612445/1
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Additional file 2: Table S6. G6PD G202A & A376G genotyping comparison. The MagPix genotyping calls were compared to data generated by TaqMan OpenArray and KASP PCR-based genotyping. Wild type calls are 202G and 376A, A- calls are 202A and 376G and A+ calls are 202G and 376G. A dot (.) denotes samples for which genotyping was unsuccessful and samples marked with a * had low net MFI values (net MFI < net MFI + 2SD). Table S7. G6PD percentage positive cells (G6PD % positive), genotyping amd CareStart G6PD RDT results for all samples from The Gambia. Samples were initially stratified by RDT result. The KASP genotypes include additional SNPs, T968C and A542T, that have been associated with decreased G6PD enzyme activity in The Gambia. The samples containing the mutant alleles are highlighted in green and the % G6PD positive cells are marked in green. Samples labelled with a * did not have a MagPix genotype assigned and hence had their KASP G6PD (G202A and A376G) used in this comparison.
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2023-06-28
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