GADD45A loss enhances leukemia-initiating cell self-renewal and ferroptosis resistance in AML

ChEBI2025-08-29 更新2026-07-12 收录

白血病干细胞

铁死亡机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-9803 数据链接链接失效反馈

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GADD45A loss enhances leukemia-initiating cell self-renewal and ferroptosis resistance in AML

创建时间：

2025-08-29

The H3K4-methyl epigenome regulates MLL leukemia stem cell oncogenic potential

白血病干细胞

表观遗传学

The genetic programs that maintain leukemia stem cell (LSC) self-renewal and oncogenic potential have been well defined, however the epigenetic landscape that determines their cellular identity and fu

NIAID Data Ecosystem70

Lack of Fzd6 in Ciliated Cells Suppresses Ferroptotic Alveolar Cell Death induced by LPS and Corona Virus. Lack of Fzd6 in Ciliated Cells Suppresses Ferroptotic Alveolar Cell Death induced by LPS and Corona Virus

铁死亡机制

肺部感染病原

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem40

DataSheet_1_Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis.zip

胰腺癌治疗

铁死亡机制

PurposeThe anti-tumour effect of Huaier has been demonstrated in a variety of tumours. Ferroptosis is a newly identified type of programmed cell death accompanied by the accumulation of reactive oxyge

NIAID Data Ecosystem20

Endoplasmic Reticulum-Targeting Quinazolinone-Based Lipophilic Probe for Specific Photoinduced Ferroptosis and Its Induced Lipid Dynamic Regulation

铁死亡机制

化学生物学

Lethal lipid peroxidation caused by reactive oxygen species occurs in different types of programmed cell death, especially in ferroptosis. Ferroptosis inducers, which serve as small-molecule probes, c

NIAID Data Ecosystem70

DataSheet_10_High expression level of the FTH1 gene is associated with poor prognosis in children with non-M3 acute myeloid leukemia.zip

AML预后标志物

铁死亡机制

Acute myelogenous leukemia (AML) is a disease that severely affects the physical health of children. Thus, we aimed to identify biomarkers associated with AML prognosis in children. Using transcriptom

NIAID Data Ecosystem30

GADD45A loss enhances leukemia-initiating cell self-renewal and ferroptosis resistance in AML

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