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IL-6 blockade prevents costimulation blockade-resistant allograft rejection by promoting intragraft regulation in T cell-depleted recipients

NIAID Data Ecosystem2026-05-02 收录

移植免疫调节

同种异体移植排斥

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE241472 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2024-06-26

肠道菌群分析

移植免疫调节

Emerging evidence has linked the gut microbiota dysbiosis to transplant rejection. Here we studied the effects of berberine on the gut microbiota of recipient mice. C57BL/6 mice transplanted with BALB

NIAID Data Ecosystem80

Study of fungiome after hematopoietic stem cell transplantation. mouse gut metagenome

肠道真菌组学

移植免疫调节

Graft-versus-host disease (GVHD) and infections are major obstacles to perform allogeneic hematopoietic stem cell transplantation. Previously, anti fungal therapy ameliorated graft-versus host disease

NIAID Data Ecosystem40

Donor regulatory T cells rapidly adapt to recipient tissues to control acute graft-versus-host disease. Donor regulatory T cells rapidly adapt to recipient tissues to control acute graft-versus-host disease

移植免疫调节

移植物抗宿主病

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem10

The early expansion of a defective NKG2Apos/CD56dim/CD16neg NK cell subset represents a therapeutic target in haploidentical HSCT

NK细胞治疗

移植免疫调节

Natural Killer (NK) cells are the first lymphocyte population to reconstitute early after non myelo-ablative and T cell-replete haploidentical hematopoietic stem cell transplantations (h-HSCTs) with p

NIAID Data Ecosystem60

Tfr Cells Restrain Rejection of Kidney Allografts by Limiting Pro-Inflammatory Cytokines in B cells [scRNA-seq]. Tfr Cells Restrain Rejection of Kidney Allografts by Limiting Pro-Inflammatory Cytokines in B cells [scRNA-seq]

移植免疫调节

单细胞RNA测序

Pathogenic antibodies produced by alloreactive B cells mediate antibody-mediated rejection (ABMR) after kidney transplantation, but the mechanisms controlling these antibodies remain poorly understood

NIAID Data Ecosystem20

IL-6 blockade prevents costimulation blockade-resistant allograft rejection by promoting intragraft regulation in T cell-depleted recipients

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