Exosomal miRNA profiling of plasma- and saliva-derived exosomes. Exosomal miRNA profiling of plasma- and saliva-derived exosomes

Exosomes were isolated from plasma and saliva of healthy individuals and head and neck cancer (HNSCC) patients. miRNA profiling of plasma- and saliva-derived exosomes was performed using nCounter SPRINT system. Diagnostic panels were selected from the exosomal miRNA profile. Overall design: Exosomal miRNA profiles from plasma and saliva of healthy individuals (n=5) and head and neck cancer patients (n=11) were analyzed regarding their diagnostic and prognostic potential, correlated to clinical data and integrated into network analysis.