Crystal structure of human RIPK1 kinase domain in complex with compound SKLB923
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Crystal structure of human RIPK1 kinase domain in complex with compound SKLB923 Descriptor: 5-[2-(cyclopropylcarbonylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-(3-fluorophenyl)ethyl]-1-methyl-indole-3-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1 Authors: Zhang, L, Wang, Y, Li, Y, Yang, S. Deposit date: 2022-04-26 Release date: 2023-04-26 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.376 Å) Cite: From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases. J.Med.Chem., 67, 2024
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2022-04-26
