RNA sequencing in arthritic joints of wild type and Sema3B deficient mice

We found that the severity of the K/BxN serum-transfer arthritis model is higher in Sema3B deficient (Sema3b-/-) mice. Here we analyzed by RNAseq the tranciptional differences in the joints of these mice group. We used four groups: 1) WT control (non-arthritic); 2) Sema3b-/- control; 3) WT arthritis day 9; 4) Sema3b-/- artritis day 9. Overall design: Forepaws mRNA profiles of control and arthrititic wild type (WT) and Sema3b-/- mice