LincK promotes proliferation and epithelial-to-mesenchymal transition and contributes to tumorigenesis and growth in breast cancer II. LincK promotes proliferation and epithelial-to-mesenchymal transition and contributes to tumorigenesis and growth in breast cancer II

We previously reported that transwell co-culture with hAD-MSCs cells can induce an EMT progress in MCF7 cells. To identify EMT-relevant lncRNAs, we conducted transcriptome microarray analysis of MCF7 cells at Day 0, 2, 4, 6, 8 and 10 after coculture. Overall design: Time course microarray experiments, MCF-7 cells cultured alone (0 day) and co-cultured with hAD-MSCs for indicated times (2, 4, 6, 8 and 10days).Total RNA was extracted with Trizol and hybridized to custom lncRNA microarray