IFNα inhibits allergic memory Th2 cells
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA524375
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资源简介：
Memory Th2 cells play an important role in allergic disease persistence and recurrence. We previously found Type I Interferon (IFN-α/β) suppressed Th2 development and stability in CD4+ T cells from healthy subjects. The aim of this study was to investigate the role of IFN-α on allergic memory Th2 cells. We recruited allergic and nonallergic subjects. Memory T cells (CD4+CD45RO+, Tm) were isolated from blood and treated with ± IFN-α for 7 days in vitro. RNASeq analysis was performed to identify differences in transcriptome profiles between nonallergic and allergic Tm activated with IFN-α
创建时间：
2019-02-26
