Myo9a

Predicted to enable actin filament binding activity and microfilament motor activity. Involved in postsynaptic specialization organization and regulation of neuron projection arborization. Located in axonal growth cone. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Used to study focal segmental glomerulosclerosis and obstructive hydrocephalus. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome. Orthologous to human MYO9A (myosin IXA). [provided by Alliance of Genome Resources, Nov 2024]

预计可激活肌动蛋白微丝结合活性及微丝马达活性。参与突触后特殊化组织构建及神经元投射树突化调节。位于轴突生长锥。在沙弗尔侧支-CA1突触中活跃。表达于多个结构中，包括消化系统、泌尿生殖系统、肢体、神经系统及感觉器官。用于研究局灶性节段性肾小球硬化症及阻塞性脑积水。此基因的人类同源基因与先天性重症肌无力综合征有关。与人类MYO9A（肌球蛋白IXA）同源。[由基因组资源联盟提供，2024年11月]