Patterns of aberrant DNA methylation after toxicant-induced malignant transformation

ChEBI2012-06-25 更新2026-07-21 收录

表观遗传学

癌症甲基化

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-38930 数据链接链接失效反馈

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Patterns of aberrant DNA methylation after toxicant-induced malignant transformation

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2012-06-25

DOT1L controls NK cell maturation and lineage integrity [RNA-seq D0 & D2]. DOT1L controls NK cell maturation and lineage integrity [RNA-seq D0 & D2]

细胞免疫学

表观遗传学

Epigenetic modifiers are promising targets to improve therapies in patients with cancer. Targeting the methyltransferase DOT1L with small molecule inhibitors has shown promising effects on the control

NIAID Data Ecosystem40

Hypo-acetylated Genes of Mouse Clone (C1)

表观遗传学

ChIP-qPCR

The change in acetylation is displayed as both percent change (%) and log (base2) values for the C1 animal relative to D1. Each value represents the average of two replicates ChIP-qPCR assays.

NIAID Data Ecosystem30

Imaging data 3 (Embryonic Stages) from "Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila" by Fitz-James et al.

胚胎发育成像

表观遗传学

Imaging data across Embryonic Stages from Figure S7 of "Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila" by Fitz-James et al.

Mendeley Data00

The five significant canonical pathways related to changes in the methylation patterns for each tissues type.

甲基化通路富集分析

表观遗传学

The log (p-value) of each pathway was determined using Fisher’s exact test. The ratios were calculated as the number of input molecules mapped to a specific pathway divided by the total number of mole

NIAID Data Ecosystem30

Additional file 8: of Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites

表观遗传学

年龄相关疾病

Table S6. Top enrichment results of age-associated differentially hypermethylated CpG positions (aDMPs) for age-related diseases and quantitative traits. (XLSX 12 kb)

Figshare2019-08-19 更新00

Patterns of aberrant DNA methylation after toxicant-induced malignant transformation

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