Despite major advances in the β-lactamase inhibitor field, certain enzymes remain refractory to inhibition by agents recently introduced. Most important among these are the class B (metallo) enzyme ND

NIAID Data Ecosystem40

Structure of metallo beta lactamase VIM-2 with cyclic boronate APC308.

β-内酰胺酶抑制剂

细菌耐药性机制

Structure of metallo beta lactamase VIM-2 with cyclic boronate APC308. Descriptor: (3~{R})-2,2-bis(oxidanyl)-3-(phenylmethylsulfanyl)-3,4-dihydro-1,2-benzoxaborinin-2-ium-8-carboxylic acid, (3~{S})-2,

Protein Data Bank Japan2024-01-24 更新30

Distinct Substrate Selectivity of a Metabolic Hydrolase from Mycobacterium tuberculosis

结核分枝杆菌酶

酶底物特异性分析

The transition between dormant and active Mycobacterium tuberculosis infection requires reorganization of its lipid metabolism and activation of a battery of serine hydrolase enzymes. Among these seri

Figshare2016-02-16 更新50

Crystal structure of chorismate synthase from Mycobacterium tuberculosis at 2.22 angstrons of resolution

蛋白质晶体

结核分枝杆菌酶

Crystal structure of chorismate synthase from Mycobacterium tuberculosis at 2.22 angstrons of resolution Descriptor: Chorismate synthase Authors: Dias, M.V.B, dos Santos, B.B, Ely, F, Basso, L.A, Sant

Protein Data Bank Japan2023-10-25 更新40

Structure of BlaC from Mycobacterium tuberculosis in complex with vaborbactam

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