首页/数据集/Genetic dissection of a super enhancer controlling the Nppa-Nppb locus in the heart (CUT&RUN)

Genetic dissection of a super enhancer controlling the Nppa-Nppb locus in the heart (CUT&RUN)

NIAID Data Ecosystem2026-03-12 收录

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CUT&RUN表观基因组学

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP252215 数据链接链接失效反馈

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资源简介：

CUT&RUN H3K27ac PCM-1 sorted left ventricle of Nppa-Nppb double-knockout Overall design: CUT&RUN H3K27ac PCM-1 sorted left ventricle of 8-12 wks old Nppa-Nppb double-knockout

应用场景：

创建时间：

2021-03-03

基因表达

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Number of fish expressing a construct in a given tissue, reported as the proportion of fish alive at the experimental time point. The first worksheet shows the fish counts for the CNSs obtained from t

DataCite Commons2024-12-13 更新80

Genome-wide landscape and functional necessity of heart enhancers

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心脏疾病基因调控

Analysis of the transcriptional changes in the heart resulting from the loss of cardiac enhancers. As there remains a limited understanding of the phenotypic consequences of enhancer mutations, we exa

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The superenhancer binding factor Med1 is broadly required for optimally expressing and hypermutating IgH genes as well as for terminating their expression through locus suicide recombination

IgH基因调控

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Assembly, expression and maturation of the Immunoglobulin heavy (IgH) chain repertoire necessitates long-range 3D-interactions under regulation by the IgH locus Eµ and 3’ regulatory region (3’RR) supe

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Evolution of gene regulatory networks during human cardiogenesis

发育表观遗传学

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Here, we show through comparative epigenomic analysis the identification of enhancers and promoters that have gained activity in humans during cardiogenesis. These cis-regulatory elements (CREs) are a

NIAID Data Ecosystem70

Characterization of sequence determinants of enhancer function using natural genetic variation. Characterization of sequence determinants of enhancer function using natural genetic variation

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遗传变异效应预测

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem50