The Sydney 1000 Bowel Cancer Study and Biobank: a 10 year observational study following the treatment pathways and outcomes of 1000 patients recently diagnosed with colorectal cancer (CRC).

Interventions: Participants will be observed from the point of diagnosis, during active treatment, during short-term clinical follow-up and for up to 10 years (or until the study ends in June 2029). Data collection includes biological samples (colorectal tumour and normal tissue, blood and faecal samples), clinical management data from patient’s medical records, patient-reported questionnaires (quality of life, side effects of chemotherapy, nutrition, physical activity, anxiety and depression and lifestyle), activity count levels and completion of patient-reported data on dietary intake.