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SNON and Arkadia (RNF111) regulate TGFβ-SMAD2/3 dose-dependent responses

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE118005
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The purpose of this RNA-seq experiment was to identify Activin A target genes that were differentially expressed in wild type and Arkadia null mouse embryonic stem cells (ESC). We performed the RNA sequencing experiment in two different wt and Arkadia-/- ESC under conditions of signalling inhibition SB431542 (SB; T0) and signalling stimulation with Activin A for 3 and 6 hours (T3 and T6 respectively). RNA-sequencing performed on two wt and two Arkadia -/- mouse embryonic stem cell lines treated with receptor kinase inhibitor (SB431542) or Activin A for 3 and 6 hours.
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2019-03-19
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