PTML model of drug-nanoparticle delivery system (OK)

Figshare2019-05-30 更新2026-04-08 收录

药物递送优化

纳米颗粒生物活性预测

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https://figshare.com/articles/PTML_model_of_vit-nanoparticle_delivery_system_OK_/8143394/2 数据链接链接失效反馈

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PTML model of ChEMBL data of vitamins fused with coated nanoparticle data of biological activity.

创建时间：

2019-05-30

Gastroretentive microballoons of olmesartan medoxomil: formulation and in vitro-in vivo evaluation

药物递送优化

BCSII类药生物利用度提升

Olmesartan medoxomil, classified as BCS class II due to its poor water solubility, exhibits a low oral bioavailability of 28.6%. Microballoons of Olmesartan medoxomil were formulated using the ionotro

DataCite Commons2025-03-01 更新740

Hydrolysis Mechanism of the Linkers by Matrix Metalloproteinase‑9 Using QM/MM Calculations

酶促反应机理计算

药物递送优化

Activatable cell-penetrating peptides (ACPPs) are known to be able to decrease the cytotoxicity of cell-penetrating peptide (CPP)-based drug delivery systems. Furthermore, they can improve the targeti

NIAID Data Ecosystem40

Modeling the Detailed Conformational Effects of the Lactosylation of Hyaluronic Acid

糖化学修饰

药物递送优化

Hyaluronic acid (HA) is a natural and biocompatible polysaccharide that is able to interact with CD44 receptors to regulate inflammation, fibrosis, and tissue reconstruction. It is a suitable chemical

NIAID Data Ecosystem20

Development of optimized resveratrol/piperine-loaded phytosomal nanocomplex for isoproterenol-induced myocardial infarction treatment

药物递送优化

心肌梗死实验治疗

Cardiovascular disease is a significant and ever-growing concern, causing high morbidity and mortality worldwide. Conventional therapy is often very precarious and requires long-term usage. Several ph

Taylor & Francis Group2024-07-13 更新60

Engineering orally disintegrating tablets for buccal delivery of cilostazol with enhanced dissolution and bioavailability: a novel dual porogenic approach, in vitro characterization, and in vivo evaluation in rats.

药物递送优化

药物生物利用度

Cilostazol (CTZ), is a BCS class II drug with limited bioavailability. In the current study, orally disintegrating tablets (ODTs) for buccal delivery of CTZ were prepared by two methods; lyophilizatio

DataCite Commons2025-05-12 更新40

PTML model of drug-nanoparticle delivery system (OK)

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