LH-indced RUNX2 expression is important for luteal gene expression. Overall design: Granulosa cells were treated with Runx2 siRNA and forskolin to knockdown agonist-induced Runx2 expression. Two separ
The removal of RUNX1/2 and CBFb affects the expression of many genes involved in ovulation and CL formation in mice The ovaries of wild-type and mutant mice (granuosa cell specific Cbfb and Runx2 knoc
A surge of luteinizing hormone (LH) from the pituitary gland triggers ovulation, oocyte maturation, and luteinization for successful reproduction in mammals. Since the signaling molecules RAS and ERK1