Supplementary Material for: Optic Neuritis Following Second Administration of COVID-19 Vaccine

A 28-year-old woman presented to eye casualty with signs and symptoms suggestive of optic neuritis following a recent COVID-19 vaccination (The Moderna mRNA-1273 vaccine). The best corrected visual acuity was 6/15 in the right eye and 6/6 in the left eye with a relative afferent pupillary defect in the right eye. Following examination and investigation, she was found to fit the McDonald Criteria for Multiple Sclerosis and was commenced on disease-modifying therapy. Demyelinating events have been identified to occur following COVID-19 vaccinations. In this case we have found that The Moderna mRNA-1273 vaccine could have contributed to the development of optic neuritis following a second dose of the vaccine.