Neuronal Dot1ll is a broad mitochondrial gene-repressor associated with human brain aging via H3K79 hypermethylation II
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE185257
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资源简介：
Role of Dot1l in the transcriptional programming of midbrain dopamine neurons Examination of three groups: 1) Pitx3-Cre/+;Dot1l-+/+;Rosa-lox-stop-lox-YFP 2) Pitx3-Cre/+;Dot1l-Floxed/+;Rosa-lox-stop-lox-YFP 3) Pitx3-Cre/+;Dot1l-Floxed/Floxed/;Rosa-lox-stop-lox-YFP. Material is FACS sorted (YFP) to isolated the Pitx3-Cre positive cells ( YFP positive) (midbrain dopamine neurons) for differential gene expression analysis at developmental stage E15.75.
创建时间：
2023-01-26
