Comparison of the clinical and epidemiologic characteristics of HIV-infected and -uninfected individuals aged ≥5 years hospitalised with severe acute respiratory illness (SARI) at four sentinel surveillance sites, South Africa, 2009–2012.

OR—Odds ratio, CI—confidence interval, HIV—human immunodeficiency virus, CHBAH—Chris Hani Baragwanath Academic Hospital† HIV-infected vs uninfected†† HIV-infected vs uninfected. Odds ratios and p values shown for all variables included in the multivariable model* Asthma, other chronic lung disease, chronic heart disease (valvular heart disease, coronary artery disease, or heart failure excluding hypertension), liver disease (cirrhosis or liver failure), renal disease (nephrotic syndrome, chronic renal failure), diabetes mellitis, immunocompromising conditions excluding HIV infection (organ transplant, immunosuppressive therapy, immunoglobulin deficiency, malignancy), neurological disease (cerebrovascular accident, spinal cord injury, seizures, neuromuscular conditions) or pregnancy. Comorbidities were considered absent in cases for which the medical records stated that the patient had no underlying medical condition or when there was no direct reference to that condition.**Positive on lytA PCR***Infection with at least one of influenza, parainfluenza virus 1, 2 and 3; respiratory syncytial virus; enterovirus; human metapneumovirus; adenovirus; rhinovirus in addition to influenzaComparison of the clinical and epidemiologic characteristics of HIV-infected and -uninfected individuals aged ≥5 years hospitalised with severe acute respiratory illness (SARI) at four sentinel surveillance sites, South Africa, 2009–2012.