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LD based statistics to study the linkage disequilibrium between two unlinked loci (VDR alleles F/f, B/b, A/a and T/t and predisposing HLA-DRB1*0301, *0401, *0402 and *0405 alleles shown collectively as DR3 in the table).

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_LD_based_statistics_to_study_the_linkage_disequilibrium_between_two_unlinked_loci_VDR_alleles_F_f_B_b_A_a_and_T_t_and_predisposing_HLA_DRB1_0301_0401_0402_and_0405_alleles_shown_collectively_as_DR3_in_the_table_/543689
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#DR3+ve includes all the Predisposing Alleles i.e. DRB1*0301,*0401,*0402 and *0405.δA, δN, VA, VN and T1 calculated as shown in statistical methods.Frequencies of DR3 = 0.6, F = 0.76, F-DR3 = 0.519 f = 0.23, f-DR3 = 0.18, B = 0.59, B-DR3 = 0.425, b = 0.41, b-DR3 = 0.315, A = 0.642, A-DR3 = 0.46, a = 0.358, a-DR3 = 0.273, T = 0.624, T-DR3 = 0.444, t = 0.376, t-DR3 = 0.275 in patients and DR3 = 0.107, F = 0.78, F-DR3 = 0.105, f = 0.21, f-DR3 = 0.047, B = 0.52, B-DR3 = 0.086, b = 0.48, b-DR3 = 0.065, A = 0.59, A-DR3 = 0.094, a = 0.411, a-DR3 = 0.065, T = 0.66 T-DR3 = 0.0942, t = 0.34, t-DR3 = 0.065 in controls. Frequencies of the VDR alleles are marginally different from Table 1 depending on which samples were typed for all the four loci and HLA-DRB1 in both patients and controls.
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2015-12-02
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