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Schematic representation of the approaches for in vitro (A) and in vivo studies (B).

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Figshare2015-12-03 更新2026-04-29 收录
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(A) Primary astroglia and microglia cultures were prepared from brain tissues of neonatal mice and then subjected to LPS treatment as described in Materials and Methods. (B) To trigger a systemic innate immune response in the CNS, presymptomatic 6-month-old hTDP-43A315T mice and their non-transgenic (wild-type) littermates received intraperitoneal i.p. injection of LPS (1 mg/kg of body weight) diluted in 100 μl of saline. Mice were i.p. injected once a week for duration of two months. (PDF)
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2015-12-03
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