We used microarray to examine changes in gene expression in the absence of Csf1r in the brain and spleen. Spleen gene expression was compared to BMDM to identify splenic-specific genes. RNA was isolat
Adaptation to existence outside the womb is a key event in the life of a mammal. The absence of macrophages in rats with a homozygous mutation in the colony-stimulating factor 1 receptor (Csf1r) gene