Crystal structure of the PWWP1 domain of NSD2 bound by compound 11.
收藏Protein Data Bank Japan2025-10-01 更新2026-04-19 收录
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Crystal structure of the PWWP1 domain of NSD2 bound by compound 11. Descriptor: (2S)-1-[4-[[(3R)-1,1-bis(oxidanylidene)thiolan-3-yl]methyl-methyl-amino]-6-methyl-pyrimidin-2-yl]-N-methyl-pyrrolidine-2-carboxamide, (2S)-1-[4-[[(3S)-1,1-bis(oxidanylidene)thiolan-3-yl]methyl-methyl-amino]-6-methyl-pyrimidin-2-yl]-N-methyl-pyrrolidine-2-carboxamide, Histone-lysine N-methyltransferase NSD2 Authors: Collie, G.W. Deposit date: 2024-06-11 Release date: 2025-09-03 Last modified: 2025-10-01 Method: X-RAY DIFFRACTION (1.618 Å) Cite: Structural and Molecular Insight into the PWWP1 Domain of NSD2 from the Discovery of Novel Binders Via DNA-Encoded Library Screening. Acs Med.Chem.Lett., 16, 2025
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2024-06-11



