Quantification of occluded capillaries in rabbit skeletal muscle upon VEGF-A and CX treatment.

The number of occluded capillaries per mm2 was determined from photographs of microscopy fields from all treatment groups. These numbers ranged from 3.5 to 88.3 and were used to categorize the microscopy fields into three groups: Microscopy fields within 1st–33rd percentile, 34th–66th percentile and 67th–100th percentile, respectively. The 33rd percentile was at 15.6 and the 67th percentile at 34.6. The number of microscopy fields within each category was then determined and are displayed in the table. VEGF-A+ vehicle versus VEGF-A+ CX (1 mg/kg), Chi-square test P = 0.0002; VEGF-A+ vehicle versus VEGF-A+ CX (2 mg/kg), Chi-square test. P = 0.0033.