Cisplatin-induced decrease of mRNA length reveals functional and translated intronic-polyadenylation isoforms in the annotated 5’-untranslated region of genes [total RNA-seq]. Cisplatin-induced decrease of mRNA length reveals functional and translated intronic-polyadenylation isoforms in the annotated 5’-untranslated region of genes [total RNA-seq]

We explored the regulation of intronic polyadenylation isoforms by cisplatin, and its impact on the translatome. This was done in part by 3'-seq (see GSE119978) and Total-RNA-Seq (this data set). Overall design: To characterize intronic polyadenylation isoforms regulated by cisplatin, we performed Total-RNA-seq analyses on cisplatin- and vehicle-treated non-small cell lung cancer cells.