官方服务：
资源简介：
HDACi improves CRISPR-mediated base editing
应用场景：
创建时间：
2020-05-27
相关数据集
Development of a hRad51–Cas9 nickase fusion that mediates HDR without double-stranded breaks
Development of a hRad51–Cas9 nickase fusion that mediates HDR without double-stranded breaks - sequencing reads from mammalian cell experiments
NIAID Data Ecosystem130
Highly efficient CRISPR-mediated base editing for the gut Bacteroides spp. with pnCasBS-CBE
We constructed a pnCasBS-CBE system for base editing in the Bacteroides thetaiotaomicron to expand their genetic toolkit, which can efficiently convert a C:G to a T:A in the genome. As a functional pr
NIAID Data Ecosystem40
Generation of diffuse intrinsic pontine glioma mouse models by brainstem targeted in utero electroporation
Diffuse intrinsic pontine gliomas (DIPGs) are highly lethal childhood brain tumors. Their unique genetic makeup, pathological heterogeneity, and brainstem location all present challenges to treatment.
干细胞与再生医学数据中心2022-02-20 更新110
Homo sapiens Genome sequencing. Homo sapiens
Recently, base editors, composed of cytidine deaminase, Cas9 nickase (nCas9), and uracil DNA glycosylase inhibitor (UGI), have recently been developed to substitute a C at a target site with T without
NIAID Data Ecosystem70
