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Crystal Structure of multi-drug resistant HIV-1 protease PR-S17 with a substrate analog p2-NC in P41

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Crystal Structure of multi-drug resistant HIV-1 protease PR-S17 with a substrate analog p2-NC in P41 Descriptor: FORMIC ACID, HIV-1 protease, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide Authors: Wang, Y.-F, Agniswamy, J, Weber, I.T. Deposit date: 2019-03-01 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Highly Drug-Resistant HIV-1 Protease Mutant PRS17 Shows Enhanced Binding to Substrate Analogues. Acs Omega, 4, 2019

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2019-03-01
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