FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl [(7S)-7-({(2E)-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enoyl}amino)-2-oxo-1,2,3,4,5,6,7,9-octahydro-11,8-(azeno)-1,9-benzodiazacyclotridecin-14-yl]carbamate
收藏Protein Data Bank Japan2026-02-18 更新2026-03-21 收录
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FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl [(7S)-7-({(2E)-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enoyl}amino)-2-oxo-1,2,3,4,5,6,7,9-octahydro-11,8-(azeno)-1,9-benzodiazacyclotridecin-14-yl]carbamate Descriptor: 1,2-ETHANEDIOL, Coagulation factor XI, SULFATE ION, ... Authors: Sheriff, S. Deposit date: 2017-05-01 Release date: 2017-07-12 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency. Bioorg. Med. Chem. Lett., 27, 2017
创建时间：
2017-05-01
