Vascular Progenitors Generated from Tankyrase Inhibitor-Regulated Naive Diabetic Human iPSC Potentiate Efficient Revascularization of Ischemic Retina
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141639
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We propose that reprogramming of patient donor cells to tankyrase inhibitor-regulated naive hiPSC (N-hiPSC) improves the functionality of differentiated progenitors for subsequent regenerative therapies, and more effectively erases donor epigenetic aberrations sustained from chronic diseases such as diabetes . LIF-3i naïve reversion of conventional, primed hiPSC lines
创建时间:
2020-03-16



