Differential Gene Transcript Levels in Acute versus Convalescent KD.

aGWAS = genome wide association study identified genes that were successfully fine-mapped.I = genes identified by Ingenuity Pathway Analysis; C = control; - = Not significant.Transcript levels of eight fine-mapped genes and three genes suggested by Ingenuity Pathway Analysis (I) were compared to transcript abundance of the loading endogenous control gene 18S, (C) in paired acute (prior to IVIg treatment) and convalescent KD samples from the same individuals (n = 25). Numbers are median (S.D.) relative values compared to endogenous control and fold change (FC) calculated by median acute levels divided by median convalescent levels. For the 18S control, numbers represent the mean (S.D.) PCR cycle at detection (Ct). Significance of differential transcript levels was determined using the Wilcoxon Rank Sum Test. - = not significant.