Human GKRP bound to AMG-5980 and S6P
收藏Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4mro
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Human GKRP bound to AMG-5980 and S6P Descriptor: 2-(4-{4-[(6-aminopyridin-3-yl)sulfonyl]piperazin-1-yl}phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... Authors: St Jean, D.J, Ashton, K.S, Bartberger, M.D, Chen, J, Chmait, S, Cupples, R, Galbreath, E, Helmering, J, Jordan, S.R, Liu, L, Kunz, K, Michelsen, K, Nishimura, N, Pennington, L.D, Poon, S.F, Sivits, G, Stec, M.M, Tamayo, N, Van, G, Yang, K, Norman, M.H, Fotsch, C, LLoyd, D.J, Hale, C. Deposit date: 2013-09-17 Release date: 2014-05-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles. J.Med.Chem., 57, 2014
创建时间：
2013-09-17
