Optimization of the antimicrobial peptide Bac7 by deep mutational scanning
收藏NIAID Data Ecosystem2026-03-12 收录
官方服务：
资源简介：
We built a high-throughput optimization platform for intracellularly active antimicrobial peptides that allows rapid investigation of a large part of the antimicrobial fitness landscape. Using deep mutational scanning, we experimentally explored the sequence space of Bac7 without the need for excessive chemical synthesis and developed a highly potent bacterial ribosomal inhibitor.
创建时间：
2021-05-20
